Article
HIV-1 replication in cell lines harboring INI1/hSNF5 mutations.
Retrovirology - 31 Aug 2006
Sorin Masha, Yung Eric, Wu Xuhong, Kalpana Ganjam V
Abstract excerpt
BACKGROUND: INI1/hSNF5 is a cellular protein that directly interacts with HIV-1 integrase (IN). It is specifically incorporated into HIV-1 virions. A dominant negative mutant derived from INI1 inhibits HIV-1 replication. Recent studies indicate that INI1 is associated with pre-integration and rev...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
