Article
Inhibition of early steps of HIV-1 replication by SNF5/Ini1.
The Journal of biological chemistry - 11 Aug 2006
Maroun Marlène, Delelis Olivier, Coadou Gaël, Bader Thomas, Ségéral Emmanuel, Mbemba Gladys, Petit Caroline, Sonigo Pierre, Rain Jean-Christophe, Mouscadet Jean-François, Benarous Richard, Emiliani Stéphane
Abstract excerpt
To replicate, human immunodeficiency virus, type 1 (HIV-1) needs to integrate a cDNA copy of its RNA genome into a chromosome of the host cell, a step controlled by the viral integrase (IN) protein. Viral integration involves the participation of several cellular proteins. SNF5/Ini1, a subunit of...
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