Article
Inactivation of the SNF5 transcription factor gene abolishes the lethal phenotype induced by the expression of HIV-1 integrase in yeast.
Gene - 18 Apr 2000
Parissi V, Caumont A, Richard de Soultrait V, Dupont C H, Pichuantes S, Litvak S
Abstract excerpt
The ubiquitous human transcription factor Ini1 has been shown to interact with HIV-1 integrase (IN) and to stimulate in vitro the reactions catalyzed by this enzyme. We have previously used a yeast model to study the effect of HIV-1 IN expression (Caumont, A.B., Jamieson, G.A., Pichuantes, S., Ng...
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