Article
Analysis of complement receptor type 1 expression on red blood cells in negative phenotypes of the Knops blood group system, according to CR1 gene allotype polymorphisms.
Transfusion - 1 Jul 2010
Pham Bach-Nga, Kisserli Aymric, Donvito Béatrice, Duret Valérie, Reveil Brigitte, Tabary Thierry, Le Pennec Pierre-Yves, Peyrard Thierry, Rouger Philippe, Cohen Jacques H M
Abstract excerpt
BACKGROUND: The KN blood group system, which consists of nine antigen specificities, is located on complement receptor Type 1 (CR1/CD35). CR1, a complement regulatory protein, acts as a vehicle for immune complex clearance. CR1 exhibits a red blood cell (RBC) density polymorphism. CR1 sites on RBCs in normal individuals range from 150 to 1200 molecules per cell. CR1 density polymorphism is regulated by HindIII...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.