Article
Mutations in the yeast vacuolar ATPase result in the mislocalization of vacuolar proteins.
The Journal of experimental biology - 1 Nov 1992
Klionsky D J, Nelson H, Nelson N, Yaver D S
Abstract excerpt
The vacuolar ATPase of the yeast Saccharomyces cerevisiae acidifies the vacuolar lumen and generates an electrochemical gradient across the vacuole membrane. We have investigated the role of compartment acidification of the vacuolar system in the sorting of vacuolar proteins. Strains with chromos...
Topics
- Adenosine Triphosphatases
- Fungal Proteins
- Genes, Fungal
- Membrane Proteins
- Mutation
- Saccharomyces cerevisiae
- Solubility
- Vacuolar Proton-Translocating ATPases
- Vacuoles
