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Article

The TNF-863A allele strongly associates with anticentromere antibody positivity in scleroderma.

Arthritis and rheumatism - 1 Feb 2004

Sato Hiroe, Lagan Anna L, Alexopoulou Christina, Vassilakis Dimitris A, Ahmad Tariq, Pantelidis Panagiotis, Veeraraghavan Srihari, Renzoni Elisabetta, Denton Chris, Black Carol, Wells Athol U, du Bois Roland M, Welsh Kenneth I

Abstract excerpt

OBJECTIVE: Scleroderma is characterized by the presence of 3 predominant, yet almost mutually exclusive, antibodies: anticentromere antibody (ACA), antitopoisomerase antibody, and anti-RNA polymerase antibody. The purpose of this study was to investigate tumor necrosis factor (TNF) polymorphisms in scleroderma, with the specific aim of determining whether TNF polymorphisms would prove to be stronger markers for...

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Identifiers

PMID: 14872499
DOI: 10.1002/art.20065

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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