Close temporal relationship between onset of cancer and scleroderma in patients with RNA polymerase I/III antibodies

doi:10.1002/art.27549

Article

Close temporal relationship between onset of cancer and scleroderma in patients with RNA polymerase I/III antibodies

6 May 2010

Abstract excerpt

OBJECTIVE: This study was undertaken to examine the temporal relationship between scleroderma development and malignancy, and to evaluate whether this differs by autoantibody status among affected patients. METHODS: Study participants had a diagnosis of scleroderma, a diagnosis of cancer, cancer, an available serum sample, and a cancer pathology specimen. Sera were tested for autoantibodies against topoisomerase...

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.