Article
Association of the TNFa13 microsatellite with systemic sclerosis in Japanese patients.
Annals of the rheumatic diseases - 1 Apr 2000
Takeuchi F, Nabeta H, Füssel M, Conrad K, Frank K H
Abstract excerpt
OBJECTIVES: To elucidate the contribution of microsatellite polymorphisms of TNFa and TNFb alleles to the pathogenesis of systemic sclerosis (SSc) by comparing the allele distribution among populations with different HLA susceptibility genes in SSc. METHODS: TNFa and TNFb microsatellite polymorphisms were determined by PCR in 54 Japanese and 50 German SSc patients and in normal controls. HLA-DR genotyping was...
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