Article
Tumor necrosis factor alpha promoter-308G/A polymorphism in Mexican patients with patchy alopecia areata.
International journal of dermatology - 1 May 2012
Cristina Cantú-Salinas, Mauricio Salinas-Santander, Armando Lagos-Rodríguez, Celia Sánchez-Domínguez, Clara Rios-Ibarra, Rocío Ortiz-López, Oliverio Welsh, Jorge Ocampo-Candiani
Abstract excerpt
BACKGROUND: Alopecia areata (AA) is a chronic inflammatory condition characterized by hair loss, most frequently from the scalp. Its etiopathogenesis is currently unknown, but inflammatory traits and associations with autoimmune diseases suggest that AA shares a similar origin. The tumor necrosis factor alpha (TNFα) gene, located on chromosome 6 within the major histocompatibility complex class III gene, may...
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