Article
Atopy and bronchial hyperresponsiveness: exclusion of linkage to markers on chromosomes 11q and 6p.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 Dec 1992
Amelung P J, Panhuysen C I, Postma D S, Levitt R C, Koeter G H, Francomano C A, Bleecker E R, Meyers D A
Abstract excerpt
Previous studies have reported a familial predisposition for the development of atopy, bronchial hyperresponsiveness and clinical asthma, and therefore have suggested the presence of a heritable component to these disorders. The specific contributions of genetic and environmental factors in the pathogenesis of allergic disease and asthma have not been determined although Cookson et al. [1] have postulated linkage...
Topics
- Adult
- Alleles
- Bronchial Hyperreactivity
- Child
- Chromosomes, Human, Pair 11
- Chromosomes, Human, Pair 6
- Forced Expiratory Volume
- Genetic Linkage
- Genetic Markers
- Humans