Linkage mapping of melanoma (MLM) using 172 microsatellite markers.

doi:10.1016/s0888-7543(05)80115-6

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Article

Linkage mapping of melanoma (MLM) using 172 microsatellite markers.

Genomics - 1 Dec 1992

Nancarrow D J, Walker G J, Weber J L, Walters M K, Palmer J M, Hayward N K

Abstract excerpt

The incidence of malignant melanoma is currently increasing faster than any other cancer and in 5-12% of cases occurs in a familial context in which the disease cosegregates as an autosomal dominant trait. To identify the location of genes that predipose individuals to familial melanoma (MLM), we...

Topics

Chromosome Mapping
DNA, Satellite
Female
Genetic Linkage
Genetic Markers
Genetic Predisposition to Disease
Humans
Lod Score
Male
Melanoma
Pedigree

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