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Article

Assignment of a Locus for Familial Melanoma, MLM, to Chromosome 9p13-p22

13 Nov 1992

Abstract excerpt

Linkage analysis of ten Utah kindreds and one Texas kindred with multiple cases of cutaneous malignant melanoma (CMM) provided evidence that a locus for familial melanoma susceptibility is in the chromosomal region 9p13-p22. The genetic markers analyzed reside in a candidate region on chromosome 9p21, previously implicated by the presence of homozygous deletions in melanoma tumors and by the presence of a...

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Identifiers

PMID: 1439824
DOI: 10.1126/science.1439824

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Assignment of a Locus for Familial Melanoma, MLM, to Chromosome 9p13-p22PMID 1439824Read ↗

Localization of the 9p melanoma susceptibility locus (MLM) to a 2-cM region between D9S736 and D9S171.Semantic proximity Read ↗

Refined localization of the melanoma (MLM) gene on chromosome 9p by analysis of allelic deletions.Semantic proximity Read ↗

Confirmation of chromosome 9p linkage in familial melanoma.Semantic proximity Read ↗

Molecular definition of a chromosome 9p21 germ-line deletion in a woman with multiple melanomas and a plexiform neurofibroma: implications for 9p tumor-suppressor gene(s).Semantic proximity Read ↗

Homozygous deletions within human chromosome band 9p21 in melanoma.Semantic proximity Read ↗

Linkage analysis of extended high-risk pedigrees replicates a cutaneous malignant melanoma predisposition locus on chromosome 9q21.Semantic proximity Read ↗

Mapping of a novel ocular and cutaneous malignant melanoma susceptibility locus to chromosome 9q21.32.Semantic proximity Read ↗

Genetic basis of susceptibility to melanoma.Semantic proximity Read ↗

Evidence for three tumor suppressor loci on chromosome 9p involved in melanoma development.Semantic proximity Read ↗

Variants at the 9p21 locus and melanoma risk.Semantic proximity Read ↗

Genetic heterogeneity in familial malignant melanoma.Semantic proximity Read ↗

Mutation analysis of candidate genes in melanoma-prone families: evidence of different pathogenetic mechanisms at chromosome 9P21.Semantic proximity Read ↗

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