Article
A genetic model of malignant phase hypertension in rats.
Kidney international - 1 Feb 1995
Whitworth C E, Fleming S, Kotelevtsev Y, Manson L, Brooker G A, Cumming A D, Mullins J J
Abstract excerpt
A genetic model of malignant phase hypertension in rats is described which closely parallels the natural history of untreated human malignant phase hypertension. Although the factors initiating transition from essential hypertension to the accelerated phase in humans remain unknown, we report the characteristics of a genetically determined and reproducible phenotype which was found to result from a cross between...
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