A genetic model of malignant phase hypertension in rats.

doi:10.1038/ki.1995.66

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Article

A genetic model of malignant phase hypertension in rats.

Kidney international - 1 Feb 1995

Whitworth C E, Fleming S, Kotelevtsev Y, Manson L, Brooker G A, Cumming A D, Mullins J J

Abstract excerpt

A genetic model of malignant phase hypertension in rats is described which closely parallels the natural history of untreated human malignant phase hypertension. Although the factors initiating transition from essential hypertension to the accelerated phase in humans remain unknown, we report the...

Topics

Alleles
Animals
Animals, Genetically Modified
Blood Pressure
Disease Models, Animal
Heterozygote
Hypertension, Malignant
Male
Phenotype
Rats
Rats, Sprague-Dawley

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