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Article

The hypertensive Ren-2 transgenic rat TGR (mREN2) 27 in hypertension research Characteristics and functional aspects

1 May 1996

Abstract excerpt

Primary human hypertension is a polygenic disorder. It is the prevalent cause of cardiovascular disease leading to cardiac failure, stroke, chronic renal failure and, ultimately to death. Several genes are involved in cardiovascular control mechanisms and their genetics are complex. Experimental models which are well defined are needed to clarify the role of individual genes. The generation of the hypertensive...

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PMID: 8735183
DOI: 10.1016/0895-7061(95)00400-9

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