Article
Analysis of the substrate specificity of the Staphylococcus aureus sortase transpeptidase SrtA.
Biochemistry - 17 Feb 2004
Kruger Ryan G, Otvos Balint, Frankel Brenda A, Bentley Matthew, Dostal Patrick, McCafferty Dewey G
Abstract excerpt
The Staphylococcus aureus sortase transpeptidase SrtA isoform is responsible for the covalent attachment of virulence and colonization-associated proteins to the bacterial peptidoglycan. SrtA utilizes two substrates, undecaprenol-pyrophosphoryl-MurNAc(GlcNAc)-Ala-D-isoGlu-Lys(epsilon-Gly(5))-D-Al...
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