Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A comprehensive in vivo screen for anti-apoptotic miRNAs indicates broad capacities for oncogenic synergy.

Developmental biology - 1 Jul 2021

Bejarano Fernando, Chang Chih-Hsuan, Sun Kailiang, Hagen Joshua W, Deng Wu-Min, Lai Eric C

Abstract excerpt

microRNAs (miRNAs) are ~21-22 nucleotide (nt) RNAs that mediate broad post-transcriptional regulatory networks. However, genetic analyses have shown that the phenotypic consequences of deleting individual miRNAs are generally far less overt compared to their misexpression. This suggests that miRNA deregulation may have broader phenotypic impacts during disease situations. We explored this concept in the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Death
Share to Drosophila Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Eye Proteins

Share to Gene Regulatory Networks

Share to MicroRNAs

Share to Neuropeptides

Share to Tumor Suppressor Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 33662357
DOI: 10.1016/j.ydbio.2021.02.010
PMCID: PMC8107139

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A comprehensive in vivo screen for anti-apoptotic miRNAs indicates broad capacities for oncogenic synergy.PMID 33662357Read ↗

A genome-wide RNAi screen reveals multiple regulators of caspase activationSemantic proximity Read ↗

Functional characterization of Drosophila microRNAs by a novel in vivo library.Semantic proximity Read ↗

A genome-wide transgenic resource for conditional expression of Drosophila microRNAs.Semantic proximity Read ↗

Systematic in vivo RNAi analysis of putative components of the Drosophila cell death machinery.Semantic proximity Read ↗

Genome-wide silencing in Drosophila captures conserved apoptotic effectorsSemantic proximity Read ↗

microRNAs in Drosophila regulate cell fate by repressing single mRNA targets.Semantic proximity Read ↗

Dredd, a novel effector of the apoptosis activators reaper, grim, and hid in Drosophila.Semantic proximity Read ↗

Genome-wide RNAi analysis of growth and viability in Drosophila cells.Semantic proximity Read ↗

Genome-wide expression analysis identifies a modulator of ionizing radiation-induced p53-independent apoptosis in Drosophila melanogaster.Semantic proximity Read ↗

bantam encodes a developmentally regulated microRNA that controls cell proliferation and regulates the proapoptotic gene hid in Drosophila.Semantic proximity Read ↗

E4orf4 induces PP2A- and Src-dependent cell death in Drosophila melanogaster and at the same time inhibits classic apoptosis pathways.Semantic proximity Read ↗

Genome-wide analyses of steroid- and radiation-triggered programmed cell death in Drosophila.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.