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Lentiviral Vectors Efficiently Transduce Quiescent Mature 3T3-L1 Adipocytes

2 Jan 2004

Abstract excerpt

Obesity is associated with many serious afflictions such as cardiovascular disease, cancer, and diabetes. One of the main cellular systems used to study the underlying physiological and biological processes is the 3T3-L1 preadipocyte differentiation model. However, studies on 3T3-L1 adipocytes are hampered by the fact that genetic modification of mature adipocytes is notoriously difficult. In this report, we...

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PMID: 14759805
DOI: 10.1016/j.ymthe.2003.11.021

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