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Gene Delivery to Adipose Tissue Using Transcriptionally Targeted rAAV8 Vectors

31 Dec 2014

Abstract excerpt

In recent years, the increasing prevalence of obesity and obesity-related co-morbidities fostered intensive research in the field of adipose tissue biology. To further unravel molecular mechanisms of adipose tissue function, genetic tools enabling functional studies in vitro and in vivo are essential. While the use of transgenic animals is well established, attempts using viral and non-viral vectors to...

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PMID: 25551639
DOI: 10.1371/journal.pone.0116288

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