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Article

Neuronal localization of C1q in preclinical Alzheimer's disease.

Neurobiology of disease - 1 Feb 2004

Fonseca Maria I, Kawas Claudia H, Troncoso Juan C, Tenner Andrea J

Abstract excerpt

Complement has been postulated to contribute to inflammatory reactions associated with the neuropathology of Alzheimer's disease (AD). C1q, an initial component of the complement cascade, is associated with neuritic plaques and with neurons in the hippocampus of AD brain. Here, we report the presence of C1q in a cognitively intact subject, previously identified as preclinical AD. We compared in detail brain...

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Identifiers

PMID: 14751769
DOI: 10.1016/j.nbd.2003.09.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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