Article
Molecular analysis of PinX1 in medulloblastomas.
International journal of cancer - 20 Mar 2004
Chang Qing, Pang Jesse Chung-sean, Li Jing, Hu Landian, Kong Xiangyin, Ng Ho-keung
Abstract excerpt
Our group has previously demonstrated a high frequency of allelic loss on the short arm of chromosome 8 and identified a region of homozygous deletion of 1.41 Mb, flanked by D8S520 and D8S1130, on 8p23.1 in medulloblastomas, suggesting the presence of a tumor suppressor gene in this critical deletion region. The aim of our study was to investigate whether PinX1, a newly identified gene whose product is a potent...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
