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Article

Cardiac ErbB-1/ErbB-2 mutant expression in young adult mice leads to cardiac dysfunction.

American journal of physiology. Heart and circulatory physiology - 1 Aug 2008

Rajagopalan Viswanathan, Zucker Irving H, Jones Jocelyn A, Carlson Michaela, Ma Ying J

Abstract excerpt

Multiple factors lead to the development and maintenance of chronic heart failure. Blockade of ErbB-2 or ErbB-4 tyrosine kinase receptor signaling leads to dilated cardiomyopathy. ErbB-1 may protect the heart against stress-induced injury and its ligand; epidermal growth factor (EGF) increases my...

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Source

Identifiers

PMID: 18599591
DOI: 10.1152/ajpheart.91436.2007

Genes

EGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-18599591-2026-09-04.1. Manifest publication-graph-cohort-2026-09-04.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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