Article

Epidermal growth factor (EGF) receptor family signalling in cardiomyocyte hypertrophy and heart failure

2026-05-19

Abstract excerpt

The epidermal growth factor receptor (EGFR) family network comprises 4 receptors (EGFR, ERBB2, ERBB3, ERBB4) and numerous ligands, and is dysregulated in many cancers. Since anti-cancer drugs that target these receptors are cardiotoxic for some patients, it is important to understand the network in cardiac cells. Data from the Human Protein Atlas established that EGFR family members and their ligands are different...

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Literature Corpus work: da087947-0014-5bc6-bce0-e52cf354e2fe
DOI: 10.64898/2026.05.16.724529

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