Neuregulin-1β induces embryonic stem cell cardiomyogenesis via ErbB3/ErbB2 receptors

doi:10.1042/bj20130818

Article

Neuregulin-1β induces embryonic stem cell cardiomyogenesis via ErbB3/ErbB2 receptors

6 Jan 2014

Abstract excerpt

NRG-1β (neuregulin-1β) serves multiple functions during embryonic heart development by signalling through ErbB family receptor tyrosine kinases (ErbB2, ErbB3 and ErbB4). Previous studies reported that NRG-1β induces cardiomyogenesis of mESCs (mouse embryonic stem cells) at the later stages of differen-tiation through ErbB4 receptor activation. In the present study we systematically examined NRG-1β induction of...

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.