Article
A simple and rapid genotyping method for beta-2 receptor (beta2 AR) gene using allele specific multiplex PCR.
Journal of clinical pharmacy and therapeutics - 1 Feb 2004
Romaino S M N, Teh L K, Zilfalil B A, Thong C P, Ismail A A, Amir J, Salleh M Z, Noor A R, Ismail R
Abstract excerpt
BACKGROUND: Polymorphism of the beta2-adrenergic receptor (beta2 AR) gene is an important determinant of the function of this receptor. It affects receptor down-regulation and beta2-agonist responses. It has also been a focus of interest in attempts to elucidate the genetic basis of asthma, hypertension, obesity and cystic fibrosis. Several different techniques have been established to determine beta2 AR...
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