Article
An improved rapid genotyping method for the study of beta-2 adrenergic receptor gene polymorphisms using single tube allele specific multiplex PCR.
Journal of clinical pharmacy and therapeutics - 1 Dec 2006
Zilfalil B A, Hoh B P, Nizam M Z, Liza-Sharmini A T, Teh L K, Ismail R
Abstract excerpt
BACKGROUND: Seventeen single nucleotide polymorphisms (SNPs) have been identified so far, within the beta-2 receptor (beta(2) AR) gene. The presence of so many SNPs within the beta(2) AR gene causes a problem, for those studying beta(2) AR pharmacogenetics, in relation to which SNPs to choose. Most of the work has focused on the three common SNPs within the coding block (alleles 16, 27 and 164) and the techniques...
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