Article
Automated detection of single nucleotide polymorphism in beta-2 adrenergic receptor gene using LCx(R).
Clinica chimica acta; international journal of clinical chemistry - 1 Jun 2001
Yu H, Merchant B, Scheffel C, Yandava C, Drazen J M, Huff J
Abstract excerpt
Beta-2 adrenergic receptor (B2AR) agonists are the most widely prescribed rescue agents used in the treatment of asthma. Recent studies have indicated a relationship between a polymorphism at codon 16 of the B2AR gene, and the response to recurrent beta-agonist therapy. The B2AR polymorphism of interest involves a single nucleotide change from A to G, resulting in an amino acid change from Arginine (Arg) to...
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