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Article

Interleukin-10 promoter gene polymorphisms and susceptibility to asthma: a meta-analysis.

PloS one - 1 Jan 2013

Hyun Myung-Han, Lee Chung-Ho, Kang Min-Hyung, Park Bong-Kyung, Lee Young Ho

Abstract excerpt

OBJECTIVE: The aim of this study was to explore whether the interleukin (IL)-10 polymorphisms and their haplotypes contribute to asthma susceptibility. METHODS: MEDLINE, EMBASE and the COCHRANE library databases were utilized to identify available articles. A meta-analysis was conducted on IL-10 -1082 G/A, -819 C/T, -592 C/A polymorphisms, and their haplotypes and asthma. RESULTS: Eleven studies involving 2,215...

Topics

Asian People
Asthma
Genetic Predisposition to Disease
Haplotypes
Humans
Interleukin-10
Odds Ratio
Polymorphism, Single Nucleotide
Promoter Regions, Genetic
Publication Bias

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23335974
DOI: 10.1371/journal.pone.0053758
PMCID: PMC3546046

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