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Expression and genetic analysis of tumor necrosis factor-alpha (TNF-alpha) G-308A polymorphism in sporadic Alzheimer's disease in a Southern China population.

Brain research - 9 Jan 2009

Yang Lianhong, Lu Ruiyan, Jiang Longyuan, Liu Zhonglin, Peng Ying

Abstract excerpt

Alzheimer's disease (AD) is one of most common chronic neurodegenerative diseases in the elderly. Tumor necrosis factor-alpha (TNF-alpha) was found elevated markedly in the serum and the cerebral spinal fluid of AD patients. And the elevation of TNF-alpha was thought to be associated with the occurrence of AD in China. However, it is still unclear whether the TNF-alpha polymorphism is related to the sporadic...

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PMID: 18992723
DOI: 10.1016/j.brainres.2008.10.019

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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