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Article

Increased C-reactive protein expression exacerbates left ventricular dysfunction and remodeling after myocardial infarction.

American journal of physiology. Heart and circulatory physiology - 1 Dec 2010

Takahashi Toshiyuki, Anzai Toshihisa, Kaneko Hidehiro, Mano Yoshinori, Anzai Atsushi, Nagai Toshiyuki, Kohno Takashi, Maekawa Yuichiro, Yoshikawa Tsutomu, Fukuda Keiichi, Ogawa Satoshi

Abstract excerpt

We previously reported serum C-reactive protein (CRP) elevation after acute myocardial infarction (MI) to be associated with adverse outcomes including cardiac rupture, left ventricular (LV) remodeling, and cardiac death. Experimental studies have indicated that CRP per se has various biological actions including proinflammatory and proapoptotic effects, suggesting a pathogenic role of CRP in the post-MI...

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PMID: 20852043
DOI: 10.1152/ajpheart.00001.2010

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CRP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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