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Human Papillomavirus Type 16 and <b> <i>TP53</i> </b> Mutation in Oral Cancer

15 Jan 2004

Abstract excerpt

TP53 mutations were analyzed in 35 human papillomavirus (HPV) type 16 DNA-positive cancers of the oral cavity and oropharynx and in 35 HPV DNA-negative cancers matched by subsite, country, sex, age, and tobacco and alcohol consumption. Wild-type TP53 was found more frequently in cancer specimens that contained HPV16 DNA than in those that did not. All 14 HPV16 DNA-positive cancers in HPV16 E6 antibody-positive...

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PMID: 14744758
DOI: 10.1158/0008-5472.can-03-3284

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