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Article

Overexpression of human cystatin C in transgenic mice does not affect levels of endogenous brain amyloid Beta Peptide.

Journal of molecular neuroscience : MN - 1 Jan 2004

Pawlik Monika, Sastre Magdalena, Calero Miguel, Mathews Paul M, Schmidt Stephen D, Nixon Ralph A, Levy Efrat

Abstract excerpt

Cystatin C, an inhibitor of cysteine proteases, colocalizes with amyloid beta (Abeta) in parenchymal and vascular amyloid deposits in brains of Alzheimer's disease (AD) patients, suggesting that cystatin C has a role in AD. Cystatin C also colocalizes with beta amyloid precursor protein (betaAPP)...

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Source

Identifiers

PMID: 14742906
DOI: 10.1385/JMN:22:1-2:13

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-14742906-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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