Article
Positive and negative regulation of a SNARE protein by control of intracellular localization.
Molecular biology of the cell - 1 Apr 2004
Nakanishi Hideki, de los Santos Pablo, Neiman Aaron M
Abstract excerpt
In Saccharomyces cerevisiae, the developmentally regulated Soluble N-ethylmaleimide sensitive factor attachment protein receptor (SNARE) protein Spo20p mediates the fusion of vesicles with the prospore membrane, which is required for the formation of spores. Spo20p is subject to both positive and negative regulation by separate sequences in its aminoterminal domain. We report that the positive activity is...
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