Article
Identification of domains required for developmentally regulated SNARE function in Saccharomyces cerevisiae.
Genetics - 1 Aug 2000
Neiman A M, Katz L, Brennwald P J
Abstract excerpt
Saccharomyces cerevisiae cells contain two homologues of the mammalian t-SNARE protein SNAP-25, encoded by the SEC9 and SPO20 genes. Although both gene products participate in post-Golgi vesicle fusion events, they cannot substitute for one another; Sec9p is active primarily in vegetative cells while Spo20p functions only during sporulation. We have investigated the basis for the developmental stage-specific...
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