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Article

Interdependency of fission yeast Alp14/TOG and coiled coil protein Alp7 in microtubule localization and bipolar spindle formation.

Molecular biology of the cell - 1 Apr 2004

Sato Masamitsu, Vardy Leah, Angel Garcia Miguel, Koonrugsa Nirada, Toda Takashi

Abstract excerpt

The Dis1/TOG family plays a pivotal role in microtubule organization. In fission yeast, Alp14 and Dis1 share an essential function in bipolar spindle formation. Here, we characterize Alp7, a novel coiled-coil protein that is required for organization of bipolar spindles. Both Alp7 and Alp14 colocalize to the spindle pole body (SPB) and mitotic spindles. Alp14 localization to these sites is fully dependent upon...

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Identifiers

PMID: 14742702
DOI: 10.1091/mbc.e03-11-0837
PMCID: PMC379260

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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