Article
Effects of {gamma}-tubulin complex proteins on microtubule nucleation and catastrophe in fission yeast.
Molecular biology of the cell - 1 Jun 2005
Zimmerman Sabina, Chang Fred
Abstract excerpt
Although gamma-tubulin complexes (gamma-TuCs) are known as microtubule (MT) nucleators, their function in vivo is still poorly defined. Mto1p (also known as mbo1p or mod20p) is a gamma-TuC-associated protein that recruits gamma-TuCs specifically to cytoplasmic MT organizing centers (MTOCs) and interphase MTs. Here, we investigated gamma-TuC function by analyzing MT behavior in mto1Delta and alp4 (GCP2 homologue)...
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