Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Autocrine IL-10 partially prevents differentiation of neonatal dendritic epidermal leukocytes into Langerhans cells.

Journal of leukocyte biology - 1 Sept 2004

Chang-Rodriguez Souyet, Ecker Rupert, Stingl Georg, Elbe-Bürger Adelheid

Abstract excerpt

To test whether reduced immune responsiveness in early life may be related to the immaturity of neonatal antigen-presenting cells, we comparatively assessed the phenotypic and functional characteristics of dendritic epidermal leukocytes (DEL) and epidermal Langerhans cells (LC) in newborn (NB) and adult mice, respectively. We report that purified, 3-day-cultured DEL do not acquire the morphology and phenotype...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigen-Presenting Cells
Share to Autocrine Communication

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Size

Share to Epidermal Cells

Share to Epidermis

Share to Langerhans Cells

Share to Leukocytes

Share to Mice, Inbred C3H

Source

Identifiers

PMID: 15197230
DOI: 10.1189/jlb.0204087

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Autocrine IL-10 partially prevents differentiation of neonatal dendritic epidermal leukocytes into Langerhans cells.PMID 15197230Read ↗

Fetal and neonatal murine skin harbors Langerhans cell precursors.Semantic proximity Read ↗

Uncovering the Mysteries of Langerhans Cells, Inflammatory Dendritic Epidermal Cells, and Monocyte-Derived Langerhans Cell-Like Cells in the Epidermis.Semantic proximity Read ↗

Human embryonic epidermis contains a diverse Langerhans cell precursor pool.Semantic proximity Read ↗

Ontogeny and function of murine epidermal Langerhans cells.Semantic proximity Read ↗

A role for endogenous transforming growth factor beta 1 in Langerhans cell biology: the skin of transforming growth factor beta 1 null mice is devoid of epidermal Langerhans cells.Semantic proximity Read ↗

Langerhans cells and more: langerin-expressing dendritic cell subsets in the skin.Semantic proximity Read ↗

Autocrine/paracrine TGFβ1 is required for the development of epidermal Langerhans cellsSemantic proximity Read ↗

IL-10 controls dendritic cell-induced T-cell reactivation in the skin to limit contact hypersensitivity.Semantic proximity Read ↗

Identification of a novel population of Langerin+ dendritic cells.Semantic proximity Read ↗

Langerhans cells regulate immunity in adulthood by regulating postnatal dermal lymphatic developmentSemantic proximity Read ↗

Interleukin-10 secretion differentiates dendritic cells from human liver and skin.Semantic proximity Read ↗

Nonredundant roles of keratinocyte‐derived IL‐34 and neutrophil‐derived CSF1 in Langerhans cell renewal in the steady state and during inflammationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.