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Article

Cdk5 phosphorylation of doublecortin ser297 regulates its effect on neuronal migration.

Neuron - 22 Jan 2004

Tanaka Teruyuki, Serneo Finley F, Tseng Huang Chun, Kulkarni Ashok B, Tsai Li Huei, Gleeson Joseph G

Abstract excerpt

Mutations in the doublecortin (DCX) gene in human or targeted disruption of the cdk5 gene in mouse lead to similar cortical lamination defects in the developing brain. Here we show that Dcx is phosphorylated by Cdk5. Dcx phosphorylation is developmentally regulated and corresponds to the timing o...

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Source

Identifiers

PMID: 14741103
DOI: 10.1016/s0896-6273(03)00852-3

Genes

DCX

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14741103-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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