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Article

Phosphorylation of drebrin by cyclin-dependent kinase 5 and its role in neuronal migration.

PloS one - 1 Jan 2014

Tanabe Kazuya, Yamazaki Hiroyuki, Inaguma Yutaka, Asada Akiko, Kimura Taeko, Takahashi Junya, Taoka Masato, Ohshima Toshio, Furuichi Teiichi, Isobe Toshiaki, Nagata Koh-ichi, Shirao Tomoaki, Hisanaga Shin-ichi

Abstract excerpt

Cyclin-dependent kinase 5 (Cdk5)-p35 is a proline-directed Ser/Thr kinase which plays a key role in neuronal migration, neurite outgrowth, and spine formation during brain development. Dynamic remodeling of cytoskeletons is required for all of these processes. Cdk5-p35 phosphorylates many cytoskeletal proteins, but it is not fully understood how Cdk5-p35 regulates cytoskeletal reorganization associated with...

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Identifiers

PMID: 24637538
DOI: 10.1371/journal.pone.0092291
PMCID: PMC3956921

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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