Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genes that regulate neuronal migration in the cerebral cortex.

Epilepsy research - 1 Sept 1999

Allen K M, Walsh C A

Abstract excerpt

Malformations of cortical development are increasingly recognized as causes of mental retardation and epilepsy. However, little is known about the molecular and biochemical signals that control the proliferation, migration, and organization of the cells involved in normal cerebral cortical development. Analysis of genes required for cortical development will help elucidate the pathogenesis of some epilepsies. In...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Movement
Share to Cerebral Cortex
Share to Disease Models, Animal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Doublecortin Protein

Share to Epilepsy

Share to Mice, Mutant Strains

Share to Neurons

Share to Signal Transduction

Source

Identifiers

PMID: 10515162
DOI: 10.1016/s0920-1211(99)00048-0

Genes

DCX

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genes that regulate neuronal migration in the cerebral cortex.PMID 10515162Read ↗

Doublecortin, a brain-specific gene mutated in human X-linked lissencephaly and double cortex syndrome, encodes a putative signaling protein.Semantic proximity Read ↗

A novel CNS gene required for neuronal migration and involved in X-linked subcortical laminar heterotopia and lissencephaly syndrome.Semantic proximity Read ↗

Classical lissencephaly and double cortex (subcortical band heterotopia): LIS1 and doublecortin.Semantic proximity Read ↗

Doublecortin is required in mice for lamination of the hippocampus but not the neocortex.Semantic proximity Read ↗

Doublecortin Is the Major Gene Causing X-Linked Subcortical Laminar Heterotopia (SCLH)Semantic proximity Read ↗

Cortical neuronal migration mutants suggest separate but intersecting pathways.Semantic proximity Read ↗

Lissencephaly and the molecular basis of neuronal migration.Semantic proximity Read ↗

Cell migration and cerebral cortical developmentSemantic proximity Read ↗

Lissencephaly and subcortical band heterotopia: molecular basis and diagnosis.Semantic proximity Read ↗

Genotypically defined lissencephalies show distinct pathologies.Semantic proximity Read ↗

Molecular genetics of neuronal migration disorders.Semantic proximity Read ↗

Genotype-phenotype correlation in neuronal migration disorders and cortical dysplasiasSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.