The p53 family protein p73 provides new insights into cancer chemosensitivity and targeting.

Abstract excerpt

The p53 tumor suppressor is part of a small family of related proteins that includes two other members, p73 and p63. Interest in the p53 family members, their functions and their complex interactions and regulation, has steadily grown over recent years and does not show signs of waning. p73 is a major determinant of chemosensitivity in humans, and mutant p53 proteins carrying specific polymorphisms can induce...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Apoptosis
• Share to Drug Delivery Systems