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Article

[p53 mutations and resistance to chemotherapy: a stab in the back for p73?].

Bulletin du cancer - 1 May 2003

Soussi Thierry

Abstract excerpt

p53 gene is a member of a multigene family that includes p53, p63 and p73. The association of p73 and p63 with cell transformation has been elusive as no genetic or epigenetic alteration of these genes has been uncovered yet. Recent work has shown clearly that p73 is an essential component of the signaling pathway that lead to apoptosis after DNA damage induced by cytotoxic agents use in cancer therapy....

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Share to Apoptosis
Share to Cell Transformation, Neoplastic
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Genes, p53

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Share to Tumor Protein p73

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Source

Identifiers

PMID: 12850759

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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