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Article

Analysis of post-translational CCR8 modifications and their influence on receptor activity.

The Journal of biological chemistry - 9 Apr 2004

Gutiérrez Julio, Kremer Leonor, Zaballos Angel, Goya Iñigo, Martínez-A Carlos, Márquez Gabriel

Abstract excerpt

Post-translational modifications of the extracellular portions of receptors located in the cell membrane can contribute to modulating their biological activity. Using a mutagenesis approach in which single or multiple Tyr-to-Phe, Thr-to-Ala, Ser-to-Ala, and Asn-to-Gln substitutions were made at the appropriate positions, we analyzed the sulfation and glycosylation state of the murine CCR8 chemokine receptor, and...

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Source

Identifiers

PMID: 14736884
DOI: 10.1074/jbc.M309689200

Genes

CCR8
CCL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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