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Article

CX3CR1 tyrosine sulfation enhances fractalkine-induced cell adhesion.

The Journal of biological chemistry - 31 May 2002

Fong Alan M, Alam S Munir, Imai Toshio, Haribabu Bodduluri, Patel Dhavalkumar D

Abstract excerpt

Fractalkine is a unique CX(3)C chemokine/mucin hybrid molecule that functions like selectins in inducing the capture of receptor-expressing cells. Because of the importance of tyrosine sulfation for ligand binding of the selectin ligand PSGL1, we tested the role of tyrosine sulfation for CX(3)CR1 function in cell adhesion. Tyrosine residues 14 and 22 in the N terminus of CX(3)CR1 were mutated to phenylalanine and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 11909868
DOI: 10.1074/jbc.M201396200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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