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Genetic, cytogenetic and developmental analysis of the Drosophila melanogaster tumor suppressor gene lethal(2)tumorous imaginal discs (1(2)tid).

Differentiation; research in biological diversity - 1 Oct 1992

Kurzik-Dumke U, Phannavong B, Gundacker D, Gateff E

Abstract excerpt

Three of the twenty recessive-lethal tumor suppressor genes of Drosophila cause imaginal disc tumors in the homozygously mutated state. One of these is the lethal(2)tumorous imaginal discs (l(2)tid) gene. Histological preparations show the tumorous imaginal disc epithelium to consist of a mosaic of cells in monolayer and cells in clumped arrangement. In contrast, the wild-type imaginal disc epithelium is...

Topics

Alleles
Animals
Chromosome Mapping
Chromosome Walking
Drosophila melanogaster
Gene Expression Regulation, Neoplastic
Genes, Insect
Genes, Lethal
Genes, Tumor Suppressor
Genetic Complementation Test

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 1473626
DOI: 10.1111/j.1432-0436.1992.tb00685.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1473626-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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