Article
Early and late events in the development of human breast cancer.
Basic life sciences - 1 Jan 1991
Smith H S, Stern R, Liu E, Benz C
Abstract excerpt
We hypothesize that early events in the development of at least some human breast cancers involve faulty epithelial-mesenchymal interactions and that the stromal cells themselves play an active role in this abnormal process. In contrast, later events accelerating breast tumor progression may occur in association with genetic changes involving only the malignant epithelial cells. These conclusions arise from a...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.