Downstream events in mammary gland morphogenesis mediated by reexpression of the alpha2beta1 integrin: the role of the alpha6 and beta4 integrin subunits.

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Article

Downstream events in mammary gland morphogenesis mediated by reexpression of the alpha2beta1 integrin: the role of the alpha6 and beta4 integrin subunits.

Cancer research - 15 May 1998

Sun H, Santoro S A, Zutter M M

Abstract excerpt

Our previous studies demonstrated that reexpression of the alpha2beta1 integrin by a poorly differentiated breast carcinoma cell line, Mm5MT, resulted in dramatic reversion of a malignant phenotype to a differentiated epithelial phenotype. We hypothesized that reexpression of the alpha2beta1 inte...

Topics

Animals
Antigens, CD
Breast
Cell Adhesion
Cells, Cultured
Epithelial Cells
Female
Humans
Integrin alpha6
Integrin beta4
Integrins
Mice
Phenotype
Receptors, Collagen
Transfection
Up-Regulation

Source

Open in PubMed

Identifiers

PMID: 9605770

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9605770-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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