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Article

APOA5 gene variants, lipoprotein particle distribution, and progression of coronary heart disease: results from the LOCAT study.

Journal of lipid research - 1 Apr 2004

Talmud Philippa J, Martin Steve, Taskinen Marja-Riitta, Frick M Heikki, Nieminen Markku S, Kesäniemi Y Antero, Pasternack Amos, Humphries Steve E, Syvänne Mikko

Abstract excerpt

Animal and human studies support a role for apolipoprotein A-V (apoA-V) in triglyceride (TG) metabolism. We examined the relationship of APOA5 -1131T>C and S19W with lipid subfractions and progression of atherosclerosis in the Lopid Coronary Angiography Trial. Compared with -1131TT men (n = 242), carriers of the -1131C allele (n = 54) had significantly higher total TG (P = 0.03), reflected in significantly...

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Identifiers

PMID: 14729863
DOI: 10.1194/jlr.M300458-JLR200

Genes

APOA5

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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APOA5 gene variants, lipoprotein particle distribution, and progression of coronary heart disease: results from the LOCAT study.PMID 14729863Read ↗

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