Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Variants at the APOA5 locus, association with carotid atherosclerosis, and modification by obesity: the Framingham Study.

Journal of lipid research - 1 May 2006

Elosua Roberto, Ordovas Jose M, Cupples L Adrienne, Lai Chao-Qiang, Demissie Serkalem, Fox Caroline S, Polak Joseph F, Wolf Philip A, D'Agostino Ralph B, O'Donnell Christopher J

Abstract excerpt

Genetic variation at the apolipoprotein A5 gene (APOA5) is associated with increased triglyceride concentrations, a risk factor for atherosclerosis. Carotid intimal medial thickness (IMT) is a surrogate measure of atherosclerosis burden. We sought to determine the association of common APOA5 genetic variants with carotid IMT and stenosis. A total of 2,273 Framingham Offspring Study participants underwent carotid...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Apolipoprotein A-V
Share to Apolipoproteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Apolipoproteins A

Share to Carotid Artery, Common

Share to Carotid Artery Diseases

Share to Carotid Stenosis

Share to Obesity

Share to Ultrasonography

Source

Identifiers

PMID: 16474174
DOI: 10.1194/jlr.M500446-JLR200

Genes

APOA5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Variants at the APOA5 locus, association with carotid atherosclerosis, and modification by obesity: the Framingham Study.PMID 16474174Read ↗

APOA5 variants and metabolic syndrome in Caucasians.Semantic proximity Read ↗

Association between sequence variant of c.553 G > T in the apolipoprotein A5 gene and metabolic syndrome, insulin resistance, and carotid atherosclerosis.Semantic proximity Read ↗

APOA5 variants predispose hyperlipidemic patients to atherogenic dyslipidemia and subclinical atherosclerosis.Semantic proximity Read ↗

A promoter variant of the APOA5 gene increases atherogenic LDL levels and arterial stiffness in hypertriglyceridemic patients.Semantic proximity Read ↗

Apolipoprotein a5 gene polymorphism and risk for metabolic syndrome: a meta-analysis.Semantic proximity Read ↗

Influence of the APOA5 locus on plasma triglyceride, lipoprotein subclasses, and CVD risk in the Framingham Heart Study.Semantic proximity Read ↗

Gender-modulated impact of apolipoprotein A5 gene (APOA5) -1131T>C and c.56C>G polymorphisms on lipids, dyslipidemia and metabolic syndrome in Turkish adults.Semantic proximity Read ↗

Association between well-characterized lipoprotein-related genetic variants and carotid intimal medial thickness and stenosis: The Framingham Heart Study.Semantic proximity Read ↗

Triglyceride-mediated pathways and coronary disease: collaborative analysis of 101 studies.Semantic proximity Read ↗

Contribution of APOA5 gene variants to plasma triglyceride determination and to the response to both fat and glucose tolerance challenges.Semantic proximity Read ↗

Effects of APOA5 -1131T>C (rs662799) on fasting plasma lipids and risk of metabolic syndrome: evidence from a case-control study in China and a meta-analysis.Semantic proximity Read ↗

APOA5 gene variation interacts with dietary fat intake to modulate obesity and circulating triglycerides in a Mediterranean population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.