APOA5 genetic variants are markers for classic hyperlipoproteinemia phenotypes and hypertriglyceridemia.

doi:10.1038/ncpcardio1326

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Article

APOA5 genetic variants are markers for classic hyperlipoproteinemia phenotypes and hypertriglyceridemia.

Nature clinical practice. Cardiovascular medicine - 1 Nov 2008

Wang Jian, Ban Matthew R, Kennedy Brooke A, Anand Sonia, Yusuf Salim, Huff Murray W, Pollex Rebecca L, Hegele Robert A

Abstract excerpt

BACKGROUND: Several known candidate gene variants are useful markers for diagnosing hyperlipoproteinemia. In an attempt to identify other useful variants, we evaluated the association of two common APOA5 single-nucleotide polymorphisms across the range of classic hyperlipoproteinemia phenotypes. METHODS: We assessed plasma lipoprotein profiles and APOA5 S19W and -1131T>C genotypes in 678 adults from a single...

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Identifiers

PMID: 18779834
DOI: 10.1038/ncpcardio1326

Genes

APOA5

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.