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Article

A new strategy for the synthesis of glycoproteins.

Science (New York, N.Y.) - 16 Jan 2004

Zhang Zhiwen, Gildersleeve Jeff, Yang Yu-Ying, Xu Ran, Loo Joseph A, Uryu Sean, Wong Chi-Huey, Schultz Peter G

Abstract excerpt

Posttranslational modifications of proteins regulate many biological processes, including metabolism, signal transduction, and gene expression. The synthetic challenges associated with generating homogeneous populations of selectively modified proteins, however, have hindered detailed studies of the effects of these modifications on protein structure and function. Here, we report an approach to the...

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PMID: 14726590
DOI: 10.1126/science.1089509

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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